If you log out, you will be required to enter your username and password the next time you visit. Septic arthritis, also known as joint infection or infectious arthritis, is the invasion of a joint by an infectious agent resulting in joint inflammation. Gonococcal arthritis is a rare complication of the sexually transmitted infection (STI) gonorrhea. Chen Y, Huang Z, Fang X, Li W, Yang B, Zhang W. Diagnosis and treatment of mycoplasmal septic arthritis: a systematic review. [5], The Gram-negative coccobacillus Kingella kingae has emerged as a prime etiology of septic arthritis and osteomyelitis in children aged 6-48 months. Update to CDC’s Sexually Transmitted Diseases Treatment Guidelines 2006: Fluoroquinolones no longer recommended for treatment of gonococcal infections. Clin Microbiol Rev. Nongonococcal infectious arthritis carries a mortality of 11%. [Medline]. Pustules on the palms are another telltale sign of gonococcal arthritis, adds Chris Morris, MD, a rheumatologist with Arthritis Associates in Kingsport, Tennessee. The lesion on this patient's heel was due to the systemic dissemination of the N gonorrhoeae bacteria. [Medline]. [Medline]. Non-gonococcal urethritis (NGU) is an infection that occurs in the urethra, which is the tube that conducts urine.It may also be referred to as nonspecific urethritis (NSU). Septic arthritis from Mycoplasma should be considered in immunocompromised patients with repeated negative cultures and poor response to empiric antibiotic treatment. 61:590-4. 37(5):702-9. 2009 Feb. 35(1):63-73. . [Medline]. A person who has a prosthetic joint has greater risk of infection. Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH. Sex Transm Infect. Arthritis Rheum. [Medline]. Diseases & Conditions, 2002 Over the three decades studied, no significant time trends in the proportions of staphylococci (67%, 65%, and 64%), streptococci (14%, 21%, and 17%), or Gram-negative rods (7%, 10%, and 14%) were detected. Rheum Dis Clin North Am. Sexually Transmitted Infections (STIs). 12(4):309-14. . April 13, 2007; Accessed: July 31, 2018. World Health Organization. Neisseria gonorrhoeae paravertebral abscess. 2012 Jul. 23 (1):[Medline]. [Medline]. 17(1):93-7. Herbert S Diamond, MD Visiting Professor of Medicine, Division of Rheumatology, State University of New York Downstate Medical Center; Chairman Emeritus, Department of Internal Medicine, Western Pennsylvania Hospital Clin Microbiol Infect. [10], In addition to the common pathogen Mycobacterium tuberculosis, nontuberculous species, such as Mycobacterium kansasii, may spread from a pulmonary focus and infect a joint. This patient presented with cutaneous foot lesions that were diagnosed as a disseminated gonococcal infection. Balsa A, Martin-Mola E. Infectious arthritis I: bacterial arthritis. Arthritis, Gonococcal. This topic will discuss the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of DGI. [Medline]. Sex Transm Infect. Innate recognition by neutrophil granulocytes differs between Neisseria gonorrhoeae strains causing local or disseminating infections. Gonococcal urethritis is caused by a germ (bacterium) called Neisseria gonorrhoeae.Gonorrhoea is one type of STI. Harrington JT. Cutaneous manifestations of disseminated gonococcemia. Diseases & Conditions, 2001 2014 Oct. 81(5):438-40. Liebling MR, Arkfeld DG, Michelini GA, Nishio MJ, Eng BJ, Jin T, et al. Diseases & Conditions, encoded search term (Gonococcal Arthritis) and Gonococcal Arthritis, Notable Knuckles, Part 2: Evaluating More Conditions of the Hand, Notable Knuckles: Evaluating Arthritic Conditions of the Hand, Evaluation and Management of Septic Arthritis and Its Mimics in the Emergency Department, Proposed RA Guidelines: Maximize Methotrexate Before Switching, Turmeric Capsules Reduce Knee Osteoarthritis Pain, Small-Fiber Polyneuropathy May Underlie Dysautonomia in ME/CFS, Denosumab Favored Over Alendronate for BMD Protection in Glucocorticoid-Induced Osteoporosis, Treatment Sequence With Romosozumab Influences Osteoporosis Outcomes. [12] Irreversible loss of joint function may result if the condition is not treated immediately and for an appropriate duration. [4] If a prosthetic joint was implanted within the preceding 6 months, S epidermidis and S aureus are major pathogens. 2002 Oct. 15(4):527-44. Victoria Fernandes Sullivan, MD Fellow in Rheumatology, Walter Reed National Military Medical CenterDisclosure: Nothing to disclose. García-De La Torre I, Nava-Zavala A. Gonococcal and nongonococcal arthritis. [Medline]. BMC Infect Dis. Beatrous SV, Grisoli SB, Riahi RR, Matherne RJ, Matherne RJ. 1985 Mar 21. All material on this website is protected by copyright, Copyright © 1994-2020 by WebMD LLC. These organisms invade the joint via the following 3 pathways: Gram-positive cocci, especially Staphylococcus aureus, are the predominant etiologic agents. 307-1 ), and made definitively when N. gonorrhoeae is identified by culture or NAAT. Pustules on the palms are another telltale sign of gonococcal arthritis, adds Chris Morris, MD, a rheumatologist with Arthritis Associates in Kingsport, Tennessee. Shirtliff ME, Mader JT. 352(14):1485-7. Here are a couple of key differences: Please confirm that you would like to log out of Medscape. [Medline]. García-De La Torre I, Nava-Zavala A. Gonococcal and nongonococcal arthritis. 2006 Apr. 1994 May. J Neurosurg Spine. More detailed information about the symptoms, causes, and treatments of Gonococcal urethritis is available below. Most episodes are caused by infection caused by pathogen that enter urethra from skin around urethral opening. The foot of this patient is swollen due to gonococcal arthritis. Three-decade trends in the distribution of organisms causing septic arthritis in native joints: Single-center study of 374 cases. By 3rd parties heat and pain in a single joint associated with a decreased ability move. Infants and young children but should be considered if suggested by the patient is swollen to... Are higher in elderly individuals are at particular risk for infectious arthritis a..., Riahi RR, Matherne RJ, Matherne RJ agents, is correlated with infectious arthritis S! August 2016 ; Accessed: July 31, 2018 healthy individuals and with... 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